Synthesis of 1,5-Dideoxy-3-O-(α-D-mannopyranosyl)-1,5-imino-D-mannitol and 1,5-Dideoxy-3-O-(α-D-glucopyranosyl)-1,5-imino-D-mannitol: Powerful Inhibitors of Endomannosidase

DOI: 10.1016/S0957-4166(00)82250-8

Source and publish data:

Tetrahedron Asymmetry p. 2011 - 2024 (1993)

Update date:2022-09-26

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Authors:

Ardron, Helen

Butters, Terry D.

Platt, Frances M.

Wormald, Mark R.

Dwek, Raymond A.

et al. et al.

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Article abstract of DOI:10.1016/S0957-4166(00)82250-8

The synthesis and conformations of 3-O-methylDMJ, 3-O-(α-D-glucopyranosyl)-DMJ (Glcα1,3DMJ), and 3-O-(α-D-mannopyranosyl)-DMJ (Manα1,3DMJ) are described.Manα1,3DMJ and Glcα1,3DMJ are shown to be very powerful inhibitors of an endomannosidase.The potential

Full text of DOI:10.1016/S0957-4166(00)82250-8

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