New pyridazinones: Synthesis and correlation between structure and α-blocking activity

DOI: 10.1016/0223-5234(93)90097-X

Source and publish data:

European Journal of Medicinal Chemistry p. 647 - 651 (1993)

Update date:2022-08-03

Topics:

Authors:

Corsano Corsano

Scapicchi

Strappaghetti

Marucci Marucci

Paparelli

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(93)90097-X

The synthesis of a series of 5-(4-piperazinyl)-3(2H)-pyridazinone has been reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens.

Full text of DOI:10.1016/0223-5234(93)90097-X

Products guided by the article

Product name:2-methyl-4-chloro-5-<4-(2-phenoxyethyl)-1-piperazinyl>-3(2H)-pyridazinone

Cas No:153276-43-8

R&D Labs maybe for 153276-43-8

Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Nanyang Tianhua pharmaceutical Co.,Ltd.

Contact:+8618639816203

Address:Longsheng Industrial Park
Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
Shanghai Hanhong Scientific Co.,Ltd.

website:http://www.chemvia.com

Contact:+86-21-64541543,54280654,13918533501

Address:Jiachuan Road 245
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD

Contact:+86-576-88685096

Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.

Relevant to this article

Enzymatic β-galactosidation of modified monosaccharides: Study of the enzyme selectivity for the acceptor and its application to the synthesis of disaccharides

Doi:10.1021/jo00083a013
(1994)
Molecular complexes of diethyl N, N ′-1,3-phenyldioxalamate and resorcinols: Conformational switching through intramolecular three-centered hydrogen-bonding

Doi:10.1021/cg401500k
(2014)
Free Radical Reactions of N-Heterocyclic Compounds. XI. Reaction of 3-Methyl-pyrazolin-5-ones with Phenoxy Radicals

Doi:10.1002/prac.19933350706
(1993)
Iminopropadienones, RN=C=C=C=O : Theory and Experiment

Doi:10.1021/j100055a007
(1994)
Dynamic covalent side-chain cross-links via intermolecular oxime or hydrazone formation from bifunctional peptides and simple organic linkers

Doi:10.1002/psc.2596
(2014)
Synthesis and biological activity of the neuronal calcium channel blocker 2-amino-1-(2,5-dimethoxyphenyl)-5-trifluoromethyl benzimidazole (NS-649)

Doi:10.1016/0960-894X(96)00010-8
(1996)

Article Doi