Asymmetric 1,3-dipolar cycloaddition of nitrile oxides to new chiral acrylamides derived from (S)-indoline-2-carboxylic acid

DOI: 10.1016/S0040-4039(00)61728-8

Source and publish data:

Tetrahedron Letters p. 6063 - 6066 (1993)

Update date:2022-08-05

Topics:

Authors:

Kim Kim

Park Park

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Article abstract of DOI:10.1016/S0040-4039(00)61728-8

Asymmetric 1,3-dipolar cycloaddition of nitrile oxides to new chiral acrylamides (3a-c) is reported to give the chiral Δ²-isoxazolines with the high diastereoselectivity (up to 95:5).

Full text of DOI:10.1016/S0040-4039(00)61728-8

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Product name:(2S,3aS,7aS)-1-((R)-3-Phenyl-4,5-dihydro-isoxazole-5-carbonyl)-octahydro-indole-2-carboxylic acid ethyl ester

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