Synthesis and biological activity of 4'-thionucleosides of 2- chloroadenine

Article abstract of DOI:10.1080/15257779408009484

1,2,3,5-Tetra-O-acetyl-4-thio-D-ribofuranose, prepared from 2,3,5-tri-O- benzyl-D-ribofuranose in four steps, was converted to the corresponding 2- chloroadenine nucleoside (8), which was deoxygenated to obtain 2-chloro-2'- deoxy-4'-thioadenosine (12). Th

Full text of DOI:10.1080/15257779408009484

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Nucleosides and Nucleotides
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Synthesis and Biological Activity of 4′-
Thionucleosides of 2-Chloroadenine1
Kamal N. Tiwari a , John A. Secrist III a & John A. Montgomery a
a Organic Chemistry Research Department , Southern Research
Institute , P. O. Box 55305, Birmingham, AL, U.S.A.35255-5305
Published online: 24 Sep 2006.
To cite this article: Kamal N. Tiwari , John A. Secrist III & John A. Montgomery (1994) Synthesis and
Biological Activity of 4′-Thionucleosides of 2-Chloroadenine1 , Nucleosides and Nucleotides, 13:8,
1819-1828, DOI: 10.1080/15257779408009484
To link to this article: http://dx.doi.org/10.1080/15257779408009484
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