A convenient synthesis of chiral N-Boc-amino ethers as potential peptide bond surrogate units

Article abstract of DOI:10.1016/0040-4039(93)88092-W

Boron triflouride etherate and zinc triflate have been found to be effective catalysists for the synthetic route to chiral N-Boc-amino ethers via a Lewis acid-catalyzed ring-opening of N-acyl aziridines, derived from chiral amino acids.