Stereocontrolled enantiospecific synthesis of anticapsin

Article abstract of DOI:10.1016/0040-4020(95)98714-S

A stereocontrolled enantiospecific synthesis of the revised structure of anticapsin (3) is described. The carbonyl group of anticapsin has also been observed to be markedly electrophilic, showing a high propensity for hydration and enolisation. A possible role for the hydrated form of anticapsin during the inhibition of glucosamine synthetase is proposed.