Tetrahedron p. 10489 - 10500 (1993)
Update date:2022-08-02
Topics:
Zacharie, Boulos
Sauve, Gilles
Penney, Christopher
The properties and characteristic reactions of thioacylating reagents 1 are described.These reagents are able to introduce thioamide linkages into a growing peptide at a specific site in the sequence.The generality and efficiency of this methodology is demonstrated by the synthesis of the three monothioanalogues of tuftsin.
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