The synthesis of 6,9-difluorobenzo[g]quinoline-5,10-dione. Displacements of the fluorides by diamines which lead to 6,9- bis[(aminoalkyl)amino]benzo[g]quinoline-5,10-diones

Article abstract of DOI:10.1002/jhet.5570300619

The synthesis of 6,9-difluorobenzo[g]quinoline-5,10-dione (3b) is described. Facile ipso substitutions of the fluorides from 3b by diamines readily yield the corresponding 6,9-bis[(aminoalkyl)amino]benzo[g]quinoline- 5,10-diones 2. The analogue 2d has been synthesized by side arm modifications of dione 8a.