Cascade radical reactions in synthesis. A new radical mediated double ring expansion-cyclisation process oxime ethers

Article abstract of DOI:10.1016/S0040-4039(00)61702-1

Treatment of the acetylene substituted cyclobutanone oxime ether (1) with (Me₃Si)₃SiH leads, in one pot, to the bicycle (2, 70%) by way of a novel double ring expansion-cyclisation process involving aminyl radical intermediates.