Tetrahedron p. 8073 - 8086 (1993)
Update date:2022-07-30
Topics:
McCombie, Stuart W.
Tagat, Jayaram R.
Metz, William A.
Nazareno, Dennis
Puar, Mohindar S.
The Michael-aldol product (8) from PhSH-PhCHO-2(5H)-furanone is converted by acids to the tricyclic compound (9), without the intermediacy of the olefin (10).The podophyllotoxin analog (22) was similarly obtained.The all-trans compounds were isomerised by DBU to the cis lactones.Hydroxylated analogs (26) and (33) were produced by reacting 2-(5H)-furanone with appropriate 2-mercaptobenzophenones.Thermal rearrangement of the sulfoxide (35) initially gave the spirocyclic isomer (37), then formed dimeric products on prolonged heating.
View Moreshanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
website:http://www.zyterpharm.com
Contact:+86-18858184290
Address:West Wenyi Road, Cangqian, Yuhang
Chongqing maohuan Chemicals Co., Ltd
website:http://www.bschem.com
Contact:+86 13996103726
Address:Chongqing Nan'an District Tu Town
Contact:18698110882
Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
Valiant Fine Chemicals Co., Ltd.
Contact:+86 535 6101878/6374484
Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
Doi:10.1248/cpb.c15-00309
(2015)Doi:10.1016/j.tetlet.2006.11.083
(2007)Doi:10.1021/ja001180f
(2000)Doi:10.1016/S0040-4020(01)80237-4
(1993)Doi:10.1080/00397919408012621
(1994)Doi:10.1021/jo00088a035
(1994)
