Tetrahedron p. 8073 - 8086 (1993)
Update date:2022-07-30
Topics:
McCombie, Stuart W.
Tagat, Jayaram R.
Metz, William A.
Nazareno, Dennis
Puar, Mohindar S.
The Michael-aldol product (8) from PhSH-PhCHO-2(5H)-furanone is converted by acids to the tricyclic compound (9), without the intermediacy of the olefin (10).The podophyllotoxin analog (22) was similarly obtained.The all-trans compounds were isomerised by DBU to the cis lactones.Hydroxylated analogs (26) and (33) were produced by reacting 2-(5H)-furanone with appropriate 2-mercaptobenzophenones.Thermal rearrangement of the sulfoxide (35) initially gave the spirocyclic isomer (37), then formed dimeric products on prolonged heating.
View MoreContact:+31-24-3886056
Address:Binderskampweg 29 Unit 36
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED
Contact:86-419-2390789
Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Shanghai Goyic Pharmaceutical&Chemical Co,. Ltd
Contact:+86-021-60275964
Address:No. 528 ruiqing road
SHIJIAZHUANG AGERUO-BIOTECH CO.LTD
Contact:+86-130-2866-6699
Address:Huaian east Road 158
Zhuhai Rundu Pharmaceutical co.,Ltd
Contact:+86-756-7630755
Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Doi:10.1248/cpb.c15-00309
(2015)Doi:10.1016/j.tetlet.2006.11.083
(2007)Doi:10.1021/ja001180f
(2000)Doi:10.1016/S0040-4020(01)80237-4
(1993)Doi:10.1080/00397919408012621
(1994)Doi:10.1021/jo00088a035
(1994)
