Synthetic studies on mannostatin A and its derivatives: A new family of glycoprotein processing inhibitors

DOI: 10.1021/ja00081a017

Source and publish data:

Journal of the American Chemical Society p. 562 - 570 (1994)

Update date:2022-08-03

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Authors:

King, Stephen Bruce

Ganem, Bruce

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Article abstract of DOI:10.1021/ja00081a017

Mannostatin A (1) is a naturally-occurring α-mannosidase inhibitor whose carbocyclic structure represents a significant departure from known alkaloid-based glycosidase inhibitors. The total synthesis of 1 [(1R,2R,3R,4R,5S)-1-(methylthio)-2,3,4-trihydroxy-

Full text of DOI:10.1021/ja00081a017

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