Iodo and diiodotyrosine epoxysuccinyl derivatives as selective inhibitors of cathepsin B

DOI: 10.1016/0223-5234(93)90046-H

Source and publish data:

European Journal of Medicinal Chemistry p. 917 - 926 (1993)

Update date:2022-07-30

Topics: Inhibitors Analog Papain Cathepsin B

Authors:

Giordano

Calabretta

Gallina Gallina

Consalvi

Scandurra

Chiaia Noya

Franchini

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(93)90046-H

Eight new analogs of L-trans-epoxysuccinyl-L-leucylamido(3-methyl)butane (E-64-c) containing Phe, Tyr, Tyr(I) or Tyr(I₂) in place of Leu, were synthesized and tested as inhibitors of papain, bovine spleen cathepsin B, calpain I and II from porc

Full text of DOI:10.1016/0223-5234(93)90046-H

Products guided by the article

Product name:N-tert-butyloxycarbonyl-3-iodo-L-tyrosylamido(3-methyl)butane

Cas No:154415-71-1

R&D Labs maybe for 154415-71-1

Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
HUNAN OUYA BIOLOGICAL CO.,LTD

Contact:+8613400661290

Address:No 908,Kangwan Rd, Liuyang Economic
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.

website:http://www.sino-strong.com.cn

Contact:+86-28-82666753

Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071
ShangHai Ruiyi Medical Technology Co.,Ltd.

Contact:+86-21-54718086

Address:No951 Jianchuan RD，Minhang District

Relevant to this article

Total Synthesis of a Novel β-Glucosidase Inhibitor, Cyclophellitol Starting from D-Glucose

Doi:10.1246/cl.1994.37
(1994)
The Scope of Direct Alkylation of Gold Surface with Solutions of C₁-C₄ n-Alkylstannanes

Doi:10.1021/jacs.5b07672
(2015)
A dual-emissive phosphine-borane Lewis pair with a U-shaped linker: Impact of methylation and complexation on fluoride binding affinity

Doi:10.1021/om4011406
(2014)
Bound and Non-bound Tetracyanoethylene Radical Anion (TCNE radical anion) in Copper(I) Triphenylphosphine Complexes. The Crystal Structures of Cu(TCNE)(PPh3)3, <-(CN)Cu(PPh3)2(TCNE)Cu(PPh3)2->n and <(PPh3)3Cu(CN)Cu(PPh3)3>

Doi:10.1039/c39940000541
(1994)
Successive Michael reaction-sigmatropic rearrangement of naphthodiquinone with O-silylated ketene acetals leading to synthesis of cycloshikonin and structure-reactivity relationship for side chain of naphthazarins

Doi:10.1248/cpb.41.1549
(1993)
Multifunctionalization of Indoles: Synthesis of 3-Iodo-2-sulfonyl Indoles

Doi:10.1002/bkcs.11882
(2019)

Article Doi