Conversion of alcohols to protected guanidines using the Mitsunobu protocol

DOI: 10.1016/S0040-4039(00)79943-6

Source and publish data:

Tetrahedron Letters p. 977 - 980 (1994)

Update date:2022-08-05

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Authors:

Dodd, Dharmpal S.

Kozikowski, Alan P.

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Article abstract of DOI:10.1016/S0040-4039(00)79943-6

An efficient method for the direct conversion of alcohols to guanidines is presented. A variety of alcohols react with 1 and 2 under Mitsunobu conditions to give the corresponding guanidines in high yield.

Full text of DOI:10.1016/S0040-4039(00)79943-6

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