Derivatives of 1,10- and 4,7-Phenanthrolinaldehydes and Di(N,N-di-ethylamino)ethoxyphenanthrolines as Potential Antitumor Agents

Article abstract of DOI:10.1002/prac.19933350708

The syntheses of 1,10- and 4,7-phenanthroline derivatives having glycidyl, oxaziridinyl, N,N-diethylaminoethoxy and thiosemicarbazone groups, and related compounds are reported.Their activities against experimental human tumor cells A 549 in vitro in relation to the molecular structures are discussed.