Use of diphenylacetyl chloride as protective reagent for sugars

Article abstract of DOI:10.1055/s-1994-25413

Diphenylacetyl chloride is used as a protective reagent for methyl α-D-glucopyranoside, methyl α-D-mannopyranoside, and α,α-trehalose showing a good regioselectivity. The obtained diphenylacetyl esters were readily removed under neutral and mild conditions with N-bromosuccinimide followed by thiourea, in a one-pot reaction, in the presence of acetyl or benzoyl groups.