Novel synthesis of mercaptopurine and pentaaza-as-indacene analogues: Reaction of [bis(methylthio)methylene]malonitrile and ethyl-2-cyano-3,3-bis(methylthio)acrylate with 5-aminopyrazoles

DOI: 10.1246/bcsj.67.738

Source and publish data:

Bulletin of the Chemical Society of Japan p. 738 - 741 (1994)

Update date:2022-08-02

Topics:

Authors:

Elgemeie

El-Ezbawy

Ali Ali

Mansour Mansour

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Article abstract of DOI:10.1246/bcsj.67.738

A novel synthesis of 7-methylthiopyrazolo[1,5-a]pyrimidines via reaction of [bis(methylthio)methylene]malononitrile and ethyl 2-cyano-3,3-bis(methylthio)acrylate with 5-aminopyrazoles is reported and the synthetic potential of the method is demonstrated.

Full text of DOI:10.1246/bcsj.67.738

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