Novel synthesis of mercaptopurine and pentaaza-as-indacene analogues: Reaction of [bis(methylthio)methylene]malonitrile and ethyl-2-cyano-3,3-bis(methylthio)acrylate with 5-aminopyrazoles

DOI: 10.1246/bcsj.67.738

Source and publish data:

Bulletin of the Chemical Society of Japan p. 738 - 741 (1994)

Update date:2022-08-02

Topics:

Authors:

Elgemeie

El-Ezbawy

Ali Ali

Mansour Mansour

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/bcsj.67.738

A novel synthesis of 7-methylthiopyrazolo[1,5-a]pyrimidines via reaction of [bis(methylthio)methylene]malononitrile and ethyl 2-cyano-3,3-bis(methylthio)acrylate with 5-aminopyrazoles is reported and the synthetic potential of the method is demonstrated.

Full text of DOI:10.1246/bcsj.67.738

Products guided by the article

Product name:2-Amino-3-(4-chloro-phenylazo)-5-hydroxy-7-methylsulfanyl-pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Cas No:155375-53-4

R&D Labs maybe for 155375-53-4

Shanghai Profirst Co., Ltd.

Contact:+86-21-38122007

Address:2, Lane 1123, Kangqiao Road, Pudong New Area, Shanghai
Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China
PharmaResources(Kaiyuan)CO,.Ltd

Contact:+86-21-50720028

Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300
Hangzhou Kai Peng Biotechnology Co., Ltd.

Contact:86-571-89939007

Address:NO. 499, Wensan West Road, Xihu District, Hangzhou, 310012, China
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA

Relevant to this article

Tin-functionalized azobenzenes as nucleophiles in stille cross-coupling reactions

Doi:10.1021/jo402598u
(2014)
A Revisitation of the Clemmensen Reduction of Diosgenin. Characterization of Byproducts and their Use in the Preparation of (25R)-26-Hydroxysterols.

Doi:10.1016/S0040-4039(00)79201-X
(1993)
Ruthenium complex catalysts supported by a bis(trifluoromethyl)pyrazolyl- pyridyl-based NNN ligand for transfer hydrogenation of ketones

Doi:10.1021/om401144u
(2014)
Synthesis of 5-<<(R,S)-5-<(9-Fluorenylmethoxycarbonyl)amino>-10,11-dihydrodibenzocyclohepten-2-yl>oxy>valeric Acid (CHA) and 5-<<(R,S)-5-<(9-Fluorenylmethoxycarbonyl)amino>dibenzocyclohepten-2-yl>oxy>valeric Acid (CHE) Handles for the Solid-Phase Synthesis of C-Terminal ...

Doi:10.1021/jo00105a010
(1994)
Relevance of Conformational Constraints to the Regioselective Lithiation of Aromatic Diethers. Application to the Convenient Construction of the DEF Tricyclic Subunit of the Austalides

Doi:10.1021/jo00087a018
(1994)
Enzyme-controllable F-NMR turn on through disassembly of peptide-based nanospheres for enzyme detection

Doi:10.1039/c3ob42078g
(2014)

Article Doi