Synthesis and antitumor activity of a series of [2-substituted-4,5- bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes

Article abstract of DOI:10.1021/jm00036a013

The synthesis, physical properties, antitumor activity, structure-activity relationships, and nephrotoxicity of a series of [2-substituted-4,5- bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes are described. The 42 platinum(II) complexes having a sev