The 3-cyclobutene-1,2-dione group: Versatile template for bioisostere construction

Article abstract of DOI:10.1080/10426509608545151

The 3,4-diamino-3-cyclobutene-1,2-dione group was utilized as a unique α-amino carboxylic acid bioisostere in a series of in vivo active NMDA antagonists, which have potential as neuroprotectants. In order to investigate SAR in this series, a new free rad

Full text of DOI:10.1080/10426509608545151

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Phosphorus, Sulfur, and Silicon and
the Related Elements
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The 3-Cyclobutene-1,2-Dione
Group: Versatile Template for
Bioisostere Construction
William A. Kinney
a Wyeth-Ayerst Research , CN 8000, Princeton, NJ
08543-8000, USA
Published online: 06 Aug 2008.
To cite this article: William A. Kinney (1996) The 3-Cyclobutene-1,2-Dione Group: Versatile
Template for Bioisostere Construction, Phosphorus, Sulfur, and Silicon and the Related
Elements, 109:1-4, 305-308
To link to this article: http://dx.doi.org/10.1080/10426509608545151
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