Chemistry of Heterocyclic Compounds p. 1200 - 1205 (1993)
Update date:2022-08-03
Topics:
Remennikov, G. Ya.
Boldyrev, I. V.
Kravchenko, S. A.
Pirozhenko, V. V.
The reaction of 1-arylidene-1-nitropropan-2-ones with O-methylisourea (or benzamidine) in the presence of aluminum oxide gave 4-aryl-6-methyl-2-methoxy(phenyl)-5-nitro-1,4-dihydropyrimidines.It was shown that the reactions of the compounds synthesized with electrophilic agents proceed at the exocyclic methyl group, as well as at the N(1), N(3), and C(5) atoms of the 1,4-dihydropyrimidine fragment of the molecule.
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