New 5′-hydroxyl protecting groups for rapid internucleotide bond formation

Article abstract of DOI:10.1016/S0040-4039(00)61413-2

A variety of 5′-hydroxyl protecting groups having catalytic sites for internucleotidic bond formation have been studied. Among them, a modified dimethoxytrityl group having an imidazolylethylcarbamoyl substituent has proved to be highly effective and superior to die IDTr group previously known.