An improved synthesis of 3-methyl-5-hydroxy protected indoles

Article abstract of DOI:10.1080/00397919408011306

The synthesis of 3-methyl-5-alkoxy indoles 14 and 15 was accomplished through the use of DIBALH to effect the reductive- cyclization of an amino-nitrile intermediate. The mild conditions used to induce cyclization allowed for the use of a benzyl protectin

Full text of DOI:10.1080/00397919408011306

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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An Improved Synthesis of 3-
Methyl-5-hydroxy Protected
Indoles
Joseph P. Marino a & Clarence R. Hurt a
a Interdepartmental Program of the Departments
Medicinal Chemistry, College of Pharmacy and
The Department of Chemistry , The University of
Michigan , Ann Arbor, Michigan, 48109
Published online: 16 Feb 2007.
To cite this article: Joseph P. Marino & Clarence R. Hurt (1994) An Improved Synthesis
of 3-Methyl-5-hydroxy Protected Indoles, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 24:6, 839-848, DOI:
10.1080/00397919408011306
To link to this article: http://dx.doi.org/10.1080/00397919408011306
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