A new synthetic route to macrocycles: Synthesis of large ring enaminolactones

DOI: 10.1016/S0040-4039(00)76754-2

Source and publish data:

Tetrahedron Letters p. 1545 - 1548 (1994)

Update date:2022-07-29

Topics:

Authors:

Jourdain

Pommelet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)76754-2

Macrocyclic enaminolactones 5 are prepared in three steps from commercially available chloroalcohols 1. The cyclization step is performed by intramolecular nucleophilic addition of the hydroxy group to an aminomethyleneketene generated by thermolysis.

Full text of DOI:10.1016/S0040-4039(00)76754-2

Products guided by the article

Product name:5-{[(3-Hydroxy-propyl)-phenyl-amino]-methylene}-2,2-dimethyl-[1,3]dioxane-4,6-dione

Cas No:155373-44-7

R&D Labs maybe for 155373-44-7

Shandong Xinhua Pharmaceutical Co.,Ltd

website:http://www.xhzy.com

Contact:+86-533-2196801

Address:1 lutai road,zhangdian dis,Zibo City
Liao Cheng All Win Chemicals Co.,LTD

Contact:86+0635-2991582

Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China
Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
CHEMINN LTD.

website:http://www.cheminn.com/

Contact:86-531-67875205

Address:No.9-2,South of Shanda Road, Jinan ,China
Nanjing Fubang Chemical Co.,Ltd

Contact:+86-25-83179199

Address:5F,Tianzheng international plaza,No399 Zhongyang Road ,Nanjing China

Relevant to this article

A novel synthesis of 2-hydroxymethyl-3-phenyl-1, 4-benzodioxanes

Doi:10.1080/00397919808004893
(1998)
Synthesis, stereochemistry, and opioid receptor binding activity of heterocyclic analogues of BW373U86

Doi:10.1002/jhet.5570320622
(1995)
Recognition of mandelate stereoisomers by chiral porphyrin hosts: Prediction of stereopreference in guest binding a priori using a simple binding model?

Doi:10.1016/j.tetlet.2013.12.046
(2014)
Regioselective benzoylation of sugars mediated by excessive Bu₂SnO: Observation of temperature promoted migration

Doi:10.1016/S0040-4020(02)00661-0
(2002)
Addition of CH₃CO₂H and HBF₄ to alkynyl complexes of ruthenium(II) and osmium(II)

Doi:10.1021/om00017a026
(1994)
Green and practical synthesis of functionalised 2H-thiopyrans via one-pot multicomponent reactions of aryl isothiocyanates in water

Doi:10.3184/174751913X13844245553486
(2013)

Article Doi