Lipid A and related compounds. XXIX. Synthesis of biologically active N-acylated L-asparagine-containing D-glucosamine derivatives structurally related to lipid A

DOI: 10.1248/cpb.42.2526

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2526 - 2531 (1994)

Update date:2022-08-04

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Authors:

Suhara Suhara

Arakawa Arakawa

Ikeda Ikeda

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.42.2526

New β-N-acylated L-asparagine-linked D-glucosamine derivatives, in which the reducing unit of lipid A has been mimicked by a lipoamino acid, have been synthesized. Compounds 1 and 2 exhibit mitogenicity and nitric oxide (NO) productivity.

Full text of DOI:10.1248/cpb.42.2526

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