2,3-Pyrrolidinedicarboxylates as Neurotransmitter Conformer Mimics: Enantioselective Synthesis via Chelation-Controlled Enolate Alkylation

DOI: 10.1021/jo00088a030

Source and publish data:

Journal of Organic Chemistry p. 2467 - 2472 (1994)

Update date:2022-08-04

Topics:

Authors:

Humphrey, John M.

Bridges, Richard J.

Hart, Jill A.

Chamberlin, A. Richard

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Article abstract of DOI:10.1021/jo00088a030

Conformationally restricted analogs of naturally-occurring amino acids can serve in a variety of ways as protein structure/function probes.A diastereo- and enantioselective synthesis of the four stereoisomers of 2,3-pyrrolidinedicarboxylic acid (an analog

Full text of DOI:10.1021/jo00088a030

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