Synthesis of the Oxazole- and Diene-Containing C9-C23 Fragment of the Type A Streptogramin Antibiotics

DOI: 10.1016/S0040-4039(00)60128-4

Source and publish data:

Tetrahedron Letters p. 7371 - 7374 (1993)

Update date:2022-09-26

Topics:

Authors:

Bergdahl, Mikael

Hett, Robert

Friebe, Timothy L.

Gangloff, Anthony R.

Iqbal, Javed

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)60128-4

The right-hand portion (3) of the type A streptogramin antibiotics was synthesized in non-racemic from through use of a Horner-Wadsworth-Emmons reaction for diene construction, an asymmetric aldol condensation, and a zinc-promoted oxazole addition reactio

Full text of DOI:10.1016/S0040-4039(00)60128-4

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