A convenient synthesis of 2-methoxy-1-naphthyl sulfoxides in high enantiomeric purity. A new asymmetric synthesis of 1-benzyl-1,2,3,4-tetrahydroisoquinolines

Article abstract of DOI:10.1016/S0040-4039(00)75860-6

The synthesis of diastereomerically pure (-)-(S) methyl 2-methoxy-1-naphthalenesulfinate (5) is reported. The reaction of (5) with methylmagnesium iodode or benzylmagnesium chloride gives (+)-(R) metyl and (+)-(R) benzyl 2-methoxy-1-naphthyl sulfoxide, (7