Synthesis and anticonvulsant activity of new dibenzo[1,2]thiazepine S,S-dioxides

DOI: 10.1002/ardp.19943270306

Source and publish data:

Archiv der Pharmazie p. 157 - 161 (1994)

Update date:2022-07-29

Topics:

Authors:

Diaz Diaz

Montero Montero

Vega Vega

Darias Darias

Tello Tello

Abdallah

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Article abstract of DOI:10.1002/ardp.19943270306

A new series of 11-substituted 6,11-dihydro-6-methyl-dibenzo[c,f][l,2]thiazepine S,S-dioxides was synthesized. Some of the components show significant anticonvulsant activity in the MES, pentetrazol and strychnine tests. The more active compounds are devoid of neurotoxic effects.

Full text of DOI:10.1002/ardp.19943270306

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