Journal of Heterocyclic Chemistry p. 161 - 166 (1994)
Update date:2022-09-26
Topics:
Blache
Gueiffier
Chavignon
Teulade
Milhavet
Viols
Chapat
Dauphin
In this paper, we report the results of heterocyclizations in the pyrido[2,3-b]pyrazine series to give the pyrido[2,3-e] or [3,2-e]pyrrolo[1,2- a]pyrazine. The Clauson-Kaas reaction on 2,3-diaminopyridine is investigated; regioselectivity on the 3-amino group is shown by 1H- and 13C-nmr. Synthesis and reactivity of the original pyrazino[2,3-g]indolizine series is also reported.
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