Antipsoriatic Anthrones with Modulated Redox Properties. 2. Novel Derivatives of Chrysarobin and Isochrysarobin - Antiproliferative Activity and 5-Lipoxygenase Inhibition

DOI: 10.1021/jm00037a017

Source and publish data:

Journal of Medicinal Chemistry p. 1660 - 1669 (1994)

Update date:2022-08-04

Topics:

Authors:

Mueller, Klaus

Leukel, Peter

Ziereis, Klaus

Gawlik, Ingo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00037a017

A novel series of 2- and 3- substituted 1,8-dihydroxy-9(10H)-anthracenones were synthesized and tested for their inhibitory activity against 5-lipoxygenase (5-LO) in bovine polymorphonuclear leukocytes and the growth of human keratinocytes.Structure-activ

Full text of DOI:10.1021/jm00037a017

Products guided by the article

Product name:2-(3,4-Dimethoxy-benzyl)-1,8-dimethoxy-anthraquinone

Cas No:155920-76-6

R&D Labs maybe for 155920-76-6

Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
Shanghai doly chemical Co.,Ltd

Contact:+86-21-34716221

Address:No.328,WuHe Roard,MinHang,ShangHai China
Hangzhou Haichem Co.,Ltd.

Contact:+86-571-86025531 / 86024803

Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Shanghai Intime pharm Co.,Ltd

Contact:86-21-58226973

Address:No 351,Guoshoujing Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, China

Relevant to this article

(η⁵-Cp)Rh(III)/Ir(III) complexes with bis(chalcogenoethers) (E, E′ Ligands: E = S/Se; E′ = S/Se): Synthesis, structure, and applications in catalytic oppenauer-type oxidation and transfer hydrogenation

Doi:10.1021/om401150s
(2014)
A mild and fast continuous-flow trifluoromethylation of coumarins with the CF₃ radical derived from CF₃SO₂Na and TBHP

Doi:10.1039/c5ob01516b
(2015)
Synthesis and Charactirisation of Zirconium Complexes with the Diphosphinophosphide Ligands ^-P(CH2CH2PR2)2 (R = Me or Et); Crystal Structure of Bispentachlorohydridodizirconium(IV)

Doi:10.1039/DT9940000977
(1994)
Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging

Doi:10.1002/jlcr.3133
(2014)
Syntheses of 5-dialkylamino-1,2-oxazoles from N,N-dialkyl-β-amino-α,β,γ,δ-unsaturated thioamides

Doi:10.1007/BF00811850
(1994)
Face Selection in Claisen Rearrangements

Doi:10.1021/jo00091a010
(1994)

Article Doi