Journal of medicinal chemistry p. 2411 - 2420 (1994)
Update date:2022-08-03
Topics: In vitro in vivo Leukotriene B4 (LTB4) Receptor antagonists
Harper
Jackson
Froelich
Boyd
Aldridge
Herron
A series of (hydroxyphenyl)pyrazoles was designed by molecular modeling comparison with the LTB4 structure and prepared for evaluation as LTB4 receptor antagonists, culminating in 4-ethyl-5-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]-2-(1H-pyrazol -3- yl)p
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