Kinetic resolution of (1RS,2RS)-2-(hydroxymethyl)cyclopentanol by a biocatalytic transesterification using lipase PS

DOI: 10.1016/0957-4166(94)80038-3

Source and publish data:

Tetrahedron Asymmetry p. 751 - 754 (1994)

Update date:2022-08-05

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Authors:

Weidner Weidner

Theil Theil

Schick Schick

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Article abstract of DOI:10.1016/0957-4166(94)80038-3

The kinetic resolution of (1RS,2SR)-2-(hydroxymethyl)cyclopentanol [(1RS,2SR)-1] by a sequential lipase-catalyzed transesterification with vinyl acetate in organic solvents in the presence of lipase from Pseudomonas cepacia (lipase PS) is described. The results are compared with data for the resolution of two structurally related 1,3-diols.

Full text of DOI:10.1016/0957-4166(94)80038-3

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