Optimization of Alkylating Agent Prodrugs Derived from Phenol and Aniline Mustards: A New Clinical Candidate Prodrug (ZD2767) for Antibody-Directed Enzyme Prodrug Therapy (ADEPT)

DOI: 10.1021/jm00026a013

Source and publish data:

Journal of Medicinal Chemistry p. 5051 - 5065 (1995)

Update date:2022-09-26

Topics:

Authors:

Springer, Caroline J.

Dowell, Robert

Burke, Philip J.

Hadley, Elma

Davies, D. Huw

et al. et al.

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Article abstract of DOI:10.1021/jm00026a013

Sixteen novel potential prodrugs derived from phenol or aniline mustards and their 16 corresponding drugs with ring substitution and/or different alkylating functionalities were designed.The <<<4- View More

Full text of DOI:10.1021/jm00026a013

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