Vitamin D3 synthetic studies. A three-step procedure for the preparation of (+)-(1R,5R,6R,9R,2'R)-1-methyl-9-(6-methylhept-2-yl)-5- (phenylsulfonyl)bicyclo[4.3.0]nonane from Windaus-Grundmann ketone

Article abstract of DOI:10.1080/00397919408011498

A procedure is described for the preparation of vitamin D₃ key fragment (+)-(1R,5R,6R,9R,2'R)-1-methyl-9-(6-methylhept-2-yl)-5- (phenylsulfonyl)bicyclo[4.3.0]nonane 3 in three steps and 55% overall yield from Windaus-Grundmann ketone 5.

Full text of DOI:10.1080/00397919408011498

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Vitamin D3 Synthetic Studies.
A Three-Step Procedure
for the Preparation of (+)-
(1R,5R,6R,9R,2′R)-1-Methyl-9-
(6-methylhept-2-yl)-5-
(phenylsulfonyl)bicyclo[4.3.0]nona
from Windaus-Grundmann
Ketone
Martin C. Clasby a & Donald Craig a
a Department of Chemistry , Imperial College of
Science, Technology and Medicine , London, SW7
2AY, U.K.
Published online: 04 Jan 2007.
To cite this article: Martin C. Clasby & Donald Craig (1994) Vitamin D3 Synthetic
Studies. A Three-Step Procedure for the Preparation of (+)-(1R,5R,6R,9R,2′R)-1-
Methyl-9-(6-methylhept-2-yl)-5-(phenylsulfonyl)bicyclo[4.3.0]nonane from
Windaus-Grundmann Ketone, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 24:4, 481-488, DOI:
10.1080/00397919408011498
To link to this article: http://dx.doi.org/10.1080/00397919408011498

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