Reductiv Amination of 1,4- and 1,5-Dicarbonyl Compounds with (S)-Valine Methyl Ester. Synthesis of (S)-2-Phenylpyrrolidine and (S)-2-Phenylpiperidine

DOI: 10.1016/S0040-4039(00)77030-4

Source and publish data:

Tetrahedron Letters p. 2775 - 2778 (1994)

Update date:2022-08-05

Topics:

Authors:

Manescalchi, Francesco

Nardi, Anna R.

Savoia, Diego

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)77030-4

The reductive amination of 4-phenyl-4-oxobutanal and 5-phenyl-5-oxopentanal with (S)-valine methyl ester and sodium cyanoborohydride afforded the N-substituted (S)-2-phenylpyrrolidine (88percent d. e.) and (S)-2-phenylpiperidine (96percent d.e.), from whi

Full text of DOI:10.1016/S0040-4039(00)77030-4

Products guided by the article

Product name:(S)-3-Methyl-2-((S)-2-phenyl-piperidin-1-yl)-butyric acid methyl ester

Cas No:156271-17-9

R&D Labs maybe for 156271-17-9

Liaoyang hengye Chemical Co., Ltd.

Contact:86-419-5850866

Address:North Old Xiaoxiao Road,Yantai District, Dengta, Liaoyang, Liaoning, China
Beijing Top Science biological technology co., LTD

Contact:+86-13439059536

Address:15-1705 jre three mile, Beijing 100000,CHINA
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
SHAANXI TOP PHARM CHEMICAL CO.LTD

Contact:+86-029-85733403

Address:No.108 ,west sector,south er huan,xi'an,china
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA

Relevant to this article

Iron-Catalyzed Borylation of Aryl Ethers via Cleavage of C-O Bonds

Doi:10.1021/acs.orglett.0c00679
(2020)
Synthesis and biological evaluation of benzo[4,5]imidazo[1,2-c]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrazine derivatives as anaplastic lymphoma kinase inhibitors

Doi:10.1016/j.bmc.2014.01.007
(2014)
A synthetic route to 3-C-alkyl (or 3-C-phenyl-) 2,3-dideoxy-D-erythro- pentono-1,4-lactones: Intermediates in the synthesis of 2(3H)-furanones

Doi:10.1016/0008-6215(94)80066-9
(1994)
An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics

Doi:10.1016/j.bmc.2011.01.030
(2011)
N-Cyanomethyl-β-chloro amines: chiral building blocks for the synthesis of azacrown ethers

Doi:10.1016/j.tetlet.2006.05.046
(2006)
Studies of Bitter Peptides from Casein Hydrolyzate. IX. Syntheses and Bitter Taste of Bitter Peptide BPIa Dimer, (Arg-Gly-Pro-Pro-Phe-Ile-Val)₂ and Gly-Gly BPIa Derivatives

Doi:10.1246/bcsj.57.815
(1984)

Article Doi