Synthesis and biological testing of 4'-(dimethylamino)-17β-hydroxy-17α-(1-propynyl)benzo-11α,18-cyclo-12a,12b-dihomo-13α-etr-4-en-3-one: an interesting RU 38 486 analog

DOI: 10.1016/0039-128X(94)90026-4

Source and publish data:

Steroids p. 185 - 189 (1994)

Update date:2022-07-31

Topics:

Authors:

Ottow, Eckhard

Beier, Sybille

Elger, Walter

Fritzemeier, Karl-Heinrich

Neef, Guenter

Wiechert, Rudolf

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Article abstract of DOI:10.1016/0039-128X(94)90026-4

A partial synthesis of the title compound, 4'-(dimethylamino)-17β-hydroxy-17α-(1-propynyl)benzo<12,12a>-11α,18-cyclo-12a,12b-dihomo-13α-estr-4-en-3-one 1, is reported.The key step in this synthesis represents an intramolecular alkenylaryl radical cyclizat

Full text of DOI:10.1016/0039-128X(94)90026-4

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Product name:4'-(dimethylamino)-17-hydroxy-17-(1-propynyl)benzo(12,12a)-11,18-cyclo-12a,12b-dihomo-estr-4-en-3-one

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