Study of the regioselectivity of palladium-catalyzed monocouplings between conjugated bis(enoltriflates) and trimethylsilylacetylene

Article abstract of DOI:10.1016/S0040-4039(00)73023-1

The Z-configurated bis(enoltriflates) 2 and 7 were treated at room temperature with TMS acetylene (1.25 equiv.) in the presence of CuI (0.17 equiv.) and various palladium catalysts (0.07 equiv.), solvents, and amines to afford monocoupling products. Surpr