A facile synthesis of 3,4-disubstituted isoxazole derivatives by regioselective cleavage of pyrano[3,4-c]isoxazoles with boron trihalide

Article abstract of DOI:10.1080/00397919808004899

4,5-Dihydro-7H-pyrano[3,4-c]isoxazoles 4 were efficiently prepared by the intramolecular nitrile oxide-alkyne cycloaddition following the Michael addition of sodium alkoxide to nitroalkene. Reaction of pyrano[3,4- c]isoxazole 4 with boron trihalide result

Full text of DOI:10.1080/00397919808004899

This article was downloaded by: [University of Montana]
On: 03 April 2015, At: 18:22
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number:
1072954 Registered office: Mortimer House, 37-41 Mortimer Street,
London W1T 3JH, UK
Synthetic Communications:
An International Journal
for Rapid Communication of
Synthetic Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
A Facile Synthesis
of 3,4-Disubstituted
Isoxazole Derivatives by
Regioselective Cleavage of
Pyrano[3,4-C]Isoxazoles
with Boron Trihalide
Hyung JinKim a & Young JuLee a
a Department of Chemical Technology ,
Chonnam National University , Kwangju,
500-757, Korea
Published online: 22 Aug 2006.
To cite this article: Hyung JinKim & Young JuLee (1998) A Facile Synthesis of 3,4-
Disubstituted Isoxazole Derivatives by Regioselective Cleavage of Pyrano[3,4-
C]Isoxazoles with Boron Trihalide, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 28:19,
3527-3537, DOI: 10.1080/00397919808004899
To link to this article: http://dx.doi.org/10.1080/00397919808004899
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all
the information (the “Content”) contained in the publications on our
platform. However, Taylor & Francis, our agents, and our licensors

make no representations or warranties whatsoever as to the accuracy,
completeness, or suitability for any purpose of the Content. Any opinions
and views expressed in this publication are the opinions and views of
the authors, and are not the views of or endorsed by Taylor & Francis.
The accuracy of the Content should not be relied upon and should be
independently verified with primary sources of information. Taylor and
Francis shall not be liable for any losses, actions, claims, proceedings,
demands, costs, expenses, damages, and other liabilities whatsoever
or howsoever caused arising directly or indirectly in connection with, in
relation to or arising out of the use of the Content.
This article may be used for research, teaching, and private study
purposes. Any substantial or systematic reproduction, redistribution,
reselling, loan, sub-licensing, systematic supply, or distribution in any
form to anyone is expressly forbidden. Terms & Conditions of access
and use can be found at http://www.tandfonline.com/page/terms-and-
conditions