Synthesis and antiviral study of dihydrothieno and thianopyrimidine diones acyclic nucleosides as potential anti-HIV agents

Article abstract of DOI:10.1080/15257779408011884

Acyclic nucleosides were prepared by alkylation of dihydrothieno and thianopyrimidines diones following Vorbruggen and Niedballa's method. None of these HEPT analogues showed significant activity against Human Immunodeficiency Virus-1 (HIV-1).

Full text of DOI:10.1080/15257779408011884

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Nucleosides and Nucleotides
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Synthesis and Antiviral Study of
Dihydrothieno and Thianopyrimidine
Diones Acyclic Nucleosides As Potential
Anti-HIV Agents
Jacques Renault a , Daniel Laduree a & Max Robba a
a Centre d'Etudes et de Recherche sur le Médicament de Normandie.
U. F.R. des Sciences Pharmaceutiques, 1, rue Vaubénard, 14000,
CAEN
Version of record first published: 24 Sep 2006.
To cite this article: Jacques Renault , Daniel Laduree & Max Robba (1994): Synthesis and Antiviral
Study of Dihydrothieno and Thianopyrimidine Diones Acyclic Nucleosides As Potential Anti-HIV Agents,
Nucleosides and Nucleotides, 13:5, 1135-1145
To link to this article: http://dx.doi.org/10.1080/15257779408011884
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