Chemical and Pharmaceutical Bulletin p. 1407 - 1411 (1995)
Update date:2022-07-29
Topics:
Tanaka
Okuda
Murakami
Yoshino
Mikamiyama
Kanda
Kim -
Iwata
Formal total synthesis of (±)-aphidicolin (1) was achieved via a Lewis acid-mediated stereoselective spiroannelation reaction as a key step. The bisbenzyl acetal (2) was synthesized from the readily available dimethyl acetal (4). Treatment of 2 with trime
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Doi:10.1016/S0957-4166(00)86173-X
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