Synthesis of Benzo-Fused, 7,5- and 7,6-Fused Azepinones as Conformationally Restricted Dipeptide Mimetics

Article abstract of DOI:10.1016/0040-4039(95)00096-U

Methodology for the generation of novel conformationally restricted dipeptide mimetics 9 and 16 has been developed.The key step involved intramolecular addition of an oxonium ion to the proximal indoline/tetrahydroquinoline aromatic ring.A dramatic differ