Tetrahedron p. 8371 - 8380 (1994)
Update date:2022-09-26
Topics:
Eger
Jalalian
Schmidt
5-Bromoethynyluracil and its deoxyriboside can be prepared in good yields starting from dibromovinyluracil, which is accesible by literature methods. 5-Bromoethynyl-deoxyuridine is less effective against HSV-1 than E- (bromovinyl)-deoxyuridine but, similar to BVDU, seems to exhibit a certain selectivity toward HSV-1. Molecular calculations prove the spatial similarity of both compounds.
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Doi:10.1177/1747519820911271
(2020)Doi:10.1016/j.ejmech.2014.02.051
(2014)Doi:10.1007/BF00812707
(1994)Doi:10.1016/S0040-4039(00)78235-9
(1994)Doi:10.1016/j.ejmech.2014.02.014
(2014)Doi:10.1021/ja501815p
(2014)
