
Tetrahedron Letters p. 5239 - 5242 (1994)
Update date:2022-08-05
Topics:
Takebuchi, Ken
Hamada, Yasumasa
Shioiri, Takayuki
Synthesis of the C13-C19 unit 2 of calyculins (1) has been accomplished by use of the stereoselective aldol reaction of the aldehyde 10 from diethyl L-tartrate (3) with methyl trimethylsilyl dimethylketene acetal followed by the introduction of a cyano group as a C1-unit.
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