
Tetrahedron p. 6163 - 6172 (1994)
Update date:2022-08-03
Topics:
Krysan, Damian J.
Haight, Anthony R.
Menzia, Jerome A.
Welch, Noel
A stereocontrolled synthesis of the dihydroxyethylene dipeptide isostere, A-82768, 1 via an erythro-selective addition of a Grignard reagent to a cis α,β-epoxy aldehyde is described. The resulting erythro-epoxy alcohol was converted to the desired 3-amino
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