First total synthesis of new diglycosides, neohancoside A, and B from Cynanchum hancockianum

Article abstract of DOI:10.1016/0040-4039(96)00750-2

First total synthesis of monoterpene diglycosides, neohancosides A (1) and B (2) from Cynanchum hancockianum were achieved stereoselectively using fluoride as a glycosyl donor. The absolute configurations of 1 and 2 were determined by enzymatic degradation of synthetic intermediates.