Journal of Organic Chemistry p. 4721 - 4722 (1994)
Update date:2022-08-02
Topics:
Overhand, Mark
Hecht, Sidney M.
The antifungal agent (+)-preussin (1) was synthesized in five efficient transformations from t-Boc-(S)-phenylalanine.The key step involved the Hg(II)-mediated ring closure of ynone 4, a 5-endo-dig process.
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