Diastereoselective synthesis of actinobolin from D-glucose by application of a novel [3+3] annulation

Article abstract of DOI:10.1021/jo00094a040

The synthesis of 5,6-O-(2-propylidene)-N-desalanyl-N-[(4-methylphenyl)methanesulfonyl]a ctinobolin (37) is reported. The carbocyclic ring of 37 is constructed by a novel [3+3] annulation method involving sequential two-electron and one-electron allylation