A New Approach to the Synthesis of γ-Hydroxy-α,β-unsaturated Macrolides and (-)-Pyrenophorin by Intramolecular C=C Bond Formation with Oxidative Functionalization from ω-alkanal

Article abstract of DOI:10.1246/cl.1994.1103

The title compounds were prepared via the intramolecular condensation reaction of 12-<α-(p-chlorophenylsulfinyl)acetoxy>tridecanal(or dodecanal) or via the combination of inter- and intramolecular condensation of 5-<α-(p-chlorophenylsulfinyl)acetoxy>hexanal in the presence of piperidine.