
Tetrahedron p. 11143 - 11152 (1994)
Update date:2022-08-04
Topics:
Okita, Takaaki
Isobe, Minoru
A pentacyclic compound was synthesized as an important intermediate of antitumor antibiotic dynemicins.The key step was the intramolecular Heck reaction using catalytic Pd reagent.During the course of the synthetic studies, an unusual spiro ring compound
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Doi:10.1021/jm500126s
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(1994)