Furanolate-based strategy for sequential 2,3,4-trisubstitution of butenolide: Total synthesis of nostoclides I and II

DOI: 10.1016/0040-4039(94)80005-7

Source and publish data:

Tetrahedron Letters p. 7897 - 7900 (1994)

Update date:2022-08-04

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Authors:

Boukouvalas, John

Maltais, Francois

Lachance, Nicolas

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Article abstract of DOI:10.1016/0040-4039(94)80005-7

The first synthesis of nostoclide I (1a) and II (1b) has been accomplished in a concise, fully regio- and stereocontrolled manner by sequential 2,3,4-trisubstitution of butenolide (6) using 2-furanolates as key intermediates.

Full text of DOI:10.1016/0040-4039(94)80005-7

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