A convergent synthesis of novel conformationally restricted HIV-1 protease inhibitors

DOI: 10.1016/S0040-4039(00)77051-1

Source and publish data:

Tetrahedron Letters p. 5153 - 5156 (1994)

Update date:2022-07-30

Topics:

Authors:

Kim, B. Moon

Guare, James P.

Hanifin, Colleen M.

Arford-Bickerstaff, Deborah J.

Vacca, Joseph P.

Ball, Richard G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)77051-1

Conformationally restricted HIV-1 protease inhibitors containing the transition state hydroxyl group in pyrrolidine or piperidine ring systems were synthesized stereoselectively utilizing the inherent stereochemistry of an amino acid derivative. A converg

Full text of DOI:10.1016/S0040-4039(00)77051-1

Products guided by the article

Product name:((1S,2R)-1-Benzyl-2-hydroxy-2-vinyl-pent-4-enyl)-carbamic acid tert-butyl ester

Cas No:160002-17-5

R&D Labs maybe for 160002-17-5

QINGDAO ON-BILLION INDUSTRAIL CO.,LTD

website:http://www.obn.com.cn

Contact:+86-15005320811 +86-532-80681989

Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Okeanos Tech.Co.,LTD

Contact:+86-10-62651721

Address:29 Yongxing Road, Daxing District,Beijing China
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China

Relevant to this article

Laccase/TEMPO-mediated system for the thermodynamically disfavored oxidation of 2,2-dihalo-1-phenylethanol derivatives

Doi:10.1039/c4gc00066h
(2014)
Syntheses and solid state structures of cyclam-based copper and zinc compounds Dedicated to Professor Maria José Calhorda on the occasion of her 65th birthday.

Doi:10.1016/j.jorganchem.2013.11.015
(2014)
Partial Synthesis of Nitrogenous Brassinosteroid Analogues with Solanidane Skeleton

Doi:10.1016/S0040-4020(01)85703-3
(1994)
SpinPhox/iridium(I)-catalyzed asymmetric hydrogenation of cyclic α-alkylidene carbonyl compounds

Doi:10.1002/anie.201309521
(2014)
Polyfluoroarylation of oxazolones: Access to non-natural fluorinated amino acids

Doi:10.1039/c7cc01606a
(2017)
Highly active phosphite gold(i) catalysts for intramolecular hydroalkoxylation, enyne cyclization and furanyne cyclization

Doi:10.1039/c4cc00839a
(2014)

Article Doi